Summary of Pharmacological Effects of humic acid and sodium humate(Part 3)
Promoting Wound Healing
- Sodium humate demonstrates a superior debridement and muscle-regeneration effect on soft wounds with purulent infections. Infected somatic cells, under the stimulation and impairment by microorganisms, undergo local hypoxia-induced necrosis, releasing detrimental ions and toxins. These toxic products compromise health and expand the wound area. Upon contact with the wound surface, sodium humate eliminates metal ions and toxins through physicochemical alterations, concurrently reducing the foul odor and secretions of pus.
- Sodium humate can promptly form a protective film on the wound surface and induce microvascular constriction to achieve hemostasis. Due to the molecular structure of sodium humate, which designates it as both an oxidant and a reductant, it can separate nascent oxygen, augment intracellular respiration within cells, boost cellular metabolism, and facilitate the survival and growth of parabiotic cells, thereby effectively controlling infection.
- Sodium humate can increase platelet counts, constrict blood vessels, lower capillary permeability, reverse abnormal microcirculatory perfusion, and promote restoration to normal.
- Sodium humate can stimulate the synthesis of prostaglandins in the gastric mucosa, increase blood flow in the gastric mucosa, protect the gastric mucosa, and facilitate ulcer healing.
Effects on Immune Function
- Sodium humate can increase the weight of the spleen in mice and rabbits, expand the white pulp region, significantly increase the number of cells in the red pulp, and give rise to large macrophages, thereby enhancing the functionality of immune organs.
- Sodium humate exerts an excitatory effect on the reticuloendothelial system's function, namely, on nonspecific immune function.
- Sodium humate has an enhancing effect on humoral immune function.
- Sodium humate can elevate the lymphocyte transformation rate, exhibiting a similar effect to that of phytohemagglutinin (PHA), and participates in cellular immunity.